"What's wrong?" the people in the room naturally gathered.

Huang Mao turned an electronic screen on the real platform and said: "I saw a significant flow of potassium electrons before, and I made sure that it was detected again just now, you look at the records, the average single conductance is more than 20 picosies per meter, which is ten times greater than the single channel conductance of ordinary potassium ion channels." ”

Pisi is a unit of conductivity per meter, and it is also one of the test marks of a single channel, and ten times the conductance must be abnormal, and everyone immediately gathered around to look at the record paper.

Yang Rui looked at it for a while, and then realized what had happened.

This appears to be a trait encoded by a familial gene.

Yang Rui quickly checked in his mind and found out the 4 members of the family, and then he couldn't laugh or cry.

Huang Mao properly found the first member of the family.

This is two different things from the AAA channel envisioned by Yang Rui.

The TAA channel is the first potassium channel identified in history, and it is also the first way to cloning the guò gene. There are quite a lot of essays describing it, and it's relatively simple to do.

Yang Rui originally considered that he would first make the AA channel, and it was easy to add some things to form a standard paper.

You might even be able to copy a paragraph of the AAA channel paper that will actually be published in '87, and you might be able to publish it in Nature.

But that's how unpredictable research can be sometimes.

It's not something you can do if you want to do something.

Historically, most scientific research results, especially breakthrough scientific research results, have been unexpected surprises, and in many cases, even the result of mistakes.

It is true that the TAA gene was the first potassium channel to be discovered, but the people who discovered it did not know what they would have discovered back then.

Just like Huang Mao now, although he is mutagenic the genes of fruit flies, he doesn't know which genes he will mutagenize, or rather, after mutagenesis, he is not sure if he can find it.

After two or three months of practice, Huang Mao did not observe the uncontrolled shaking of the calf of the fruit fly (aaa) like the scientists of the time, but on the contrary, Huang Mao found a phenomenon that is not easy to observe: an increase in electrical conductance

Of course, the so-called unobservability is also relative.

The TAA gene, also known as the leg shaker gene, has a problem with this gene, and the voltage of the potassium channel of the fruit fly will also have a problem, so that when the fruit fly is stunned by ether, the calf will keep shaking.

However, so many people in Hua Ruishi's room did not know hundreds or thousands of groups of mutagenesis, or did not mutagenesis to the leg-shaking gene, or mutagenesis arrived, and there was no stunning of fruit flies at that time, and no such phenomenon was observed - this is also normal, if the phenomenon of gene mutation is so easy to observe, the biological world will not play with fruit flies for decades, and still play fruit flies in the 2l century......

In terms of the unhappiness of the population, fruit flies have poured eight more molds than mice.

In contrast, the AAA gene is easy to observe externally, while the increase in conductance observed by Huang Mao is the easiest and easiest to observe on the instrument.

Because what is being done is the potassium ion channel, observing the potassium ion conductivity is also the proper meaning, and the channel is even more special, and the surface of its gene is a 10-fold increase in conductivity.

In this way, even if the accuracy of the instrument is not high, a change of an order of magnitude is still easy to notice.

"Show me the actual record. Yang Rui's mood was still a little excited. The key to determining potassium channels is to confirm the appearance of the mutant gene.

If you describe it in words, this is a very simple process: induce a mutation in gene A, and find that the organism has a change in B, so it is natural to determine that the function of the gene is to make B unchanged.

For example, if the AAA gene is mutated, the legs of the fruit fly are shaking, so it is determined that the function of the AAA gene is to keep the legs of the fruit fly from shaking.

Doing this is actually a very good paper, but it may not necessarily be in Nature.

If you want to determine the "Nature", you have to repeat the induction process constantly, and then determine why the legs are shaking and the legs are not shaking, and finally it turns out to be a voltage problem, plus a smooth article, which is basically a good paper in "Nature". Of course, if you want to be on "Science", you have to be literary, regardless of the content, and the writing must be a bit literary and artistic......

As a young man in the field of natural science, the hairline forced back by Science can circle the earth seven and a half times when connected

Huang Mao was also excited, and quickly found a few boxes from the top cabinet, then turned out the actual records and handed them to Yang Rui.

His actual record is very detailed, which is also Yang Rui's request, or experience.

20 years later, foreign real yàn rooms are all recorded by video, and the purpose is to record the real yàn in every detail.

People who have just finished the process will remember the process very clearly, but after a few weeks, months, or years, the memory will fade very strongly.

At the end of the day, the research institute with a good memory may remember the main or secondary steps, but which instrument is used in the real yàn? Which chemical reagent is used in the real yàn? 100 out of 100 people can't remember.

If it is a long-term real product that lasts for several years, when it is re-verified or re-compared, is it difficult to do it again?

It's just to do it all over again, and the chemical reagents provided by different companies are also different, and the results are biased, and who is it?

Falling in the real yàn of the potassium channel, Yang Rui first had to determine that in the case of abnormal conductivity, the real yàn conditions did not change dramatically.

Fortunately, the conductivity of the channel changes very drastically, 10 times, which is basically difficult to affect by the outside world, which makes the audit work relatively easy.

When Yang Rui reviewed from beginning to end, Tu Xian and the others had already begun to congratulate Huang Mao.

Huang Mao himself suffered a little from gains and losses, and while looking at Yang Rui's unchanged expression with concern, he smiled and said, "Look at your red eyes, the second author is also jealous?"

"Who is jealous of you, our old Tu has also achieved results recently, isn't it?" Wang Xiaoyun has the advantage of being a woman, and she can speak much more casually.

Huang Mao deliberately laughed, changed it to a smug expression, and said: "The first paper on the potassium channel can take a big advantage, and the second article is not necessarily. ”

"With the progress of your current research, it's not certain that you can do the first one, isn't it?" Wang Xiaoyun poked her husband.

"I just need to do it, how about the paper, Yang Rui is in charge. Tu Xian ignored his wife's competitiveness.

Wang Xiaoyun punched him helplessly and said, "I'm not motivated." ”

"I'm not self-motivated to do it every day. Wei Zhenxue screamed and said, "You two in-laws are working like this, and other people's children should be in elementary school."

Wang Xiaoyun's face suddenly turned red and she didn't dare to speak. Both of them were busy in the real room, so naturally they didn't have time to give birth, which was a little different from the ordinary marriage in the 8s.

Tu Xian smiled instead and said, "Old Wei, can a single person still have children?"

Wei Zhenxue's momentum froze, he thought about it for a long time, and came up with a strange way to fight back, and said, "Do you believe that I will do IVF by myself?"

At the level of Huarui Shiy's room, there are really hardware conditions for doing IVF, and Wei Zhenxue also has the corresponding operating foundation.

However, this kind of second-class way of speaking is only available to Wei Zhenxue.

Normal people are at least looking for a big-breasted beauty or something.

Tu Xian was stunned by Wei Zhenxue's unexpected answer, and at this time, Wang Xiaoyun asked coldly: "Do you use the test tube you have filled with mung bean soup?"

"Puff ......" Sun Ruyue, a real dog who had never dared to speak, couldn't hold back anymore and snickered.

Tu Xian and Huang Mao also coughed vigorously.

Wei Zhenxue looked as usual, and said, "I've told you, the test tube is filled with mung bean porridge, and what is separated is mung bean soup." ”

……