Chapter 256: God's Blood and Genetic Engineering
Soon, Richard saw Gutas's method of suicide, which was...... Hunger strike.
Gutas was confident in this, but Richard was unimpressed.
And then......
On the first day of the hunger strike, Gutas was alive and kicking.
On the second day of his hunger strike, Gutas went on business as usual.
On the third day of the hunger strike, Gutas did not change.
The fourth day of the hunger strike.
laboratory, in the main laboratory.
Gutas was sturdyly strapped to a chair, and Richard pulled a certain amount of blood from his arm and put it in a test tube.
Turning around, he inserted a special needle into Gutas's vein, behind which was a tube and a strange device, and behind the tube was a glass bottle with a configured concentration of 0.9% saline and a 5% concentration of glucose solution.
Gutas watched Richard motionless, his eyes full of resentment.
Richard looked calm, and even smiled a little: "To be honest, you should have gone on a hunger strike two days earlier." After all, compared to eating, through infusion, only 600ml of normal saline and 120ml of glucose are needed to meet the daily needs of the human body.
Normal saline can be prepared at will, only salt and water are needed. Glucose may be a little troublesome, but it can be obtained by acid hydrolysis with some starch. No matter how you look at it, it's easier than feeding you food. Of course, it's a bit anti-human, and I didn't plan to do it in the first place, but you chose it yourself, and I can't help it, can I?
In other words, this way of sustaining life should not be too long, otherwise it will cause malnutrition. But it's okay, after a while, I can feed you liquid food by nasogastric feeding to supplement the nutrients that can't be obtained by infusion. At that time, it will be more painful to need a gastric tube, so you should be mentally prepared in advance. After all, it's all your own choice, right?"
Gutas was already a little desperate in his heart, and he fully understood a truth: if it falls into the hands of Richard, he can't die!
This...... It's total, no matter if you live or die, you won't be left behind!
Shameless!
......
In the despair of Gutas, many days passed.
Laboratory, main laboratory.
In the light of candlelight, Richard used a quill pen to quickly write the experimental codex.
"Rustling ......"
“...... The experiment was carried out well and the results were in line with expectations......"
“...... The theory obtained is slightly different from the previous one, but the direction is correct......"
“...... The hard-to-extract limit amplification hormone was injected back into the subject, and the subject produced an increase similar to the third peak of the previous experiment, while the second and first peaks were weakened. Illustrated, there is a negative feedback regulation phenomenon.
That is, the agent stimulates the body to secrete 'pro-limit hormone', and 'pro-limit hormone' stimulates the blood and blood glands to secrete 'maximum amplification hormone'. While the 'limit amplification hormone' is working, the inhibition of the 'limit amplification hormone' and the drug continue to exert its effect......"
“...... To sum up, the mechanism of action of the secret of the bloodline seed and the heroic elixir of Spartas is sorted out as follows.
When ordinary people use the drug: the drug → regulate the human body, exert an amplification effect, and release the 'pro-maximum-amplification hormone'→ termination.
When the blood seed activates the power: the blood glands → secrete 'ordinary amplification hormones' → regulate the human body, and the amplification effect → terminate.
When the Bloodline Seed activates the power and uses the potion: the potion → regulate the human body, exert an amplification effect, and release the 'Limit Amplification Hormone'→ stimulate the blood glands to secrete → 'Limit Amplification Hormone'→ regulate the human body, exert the third peak amplification effect, and the ability to burst beyond the limit of the human body → terminated.
......”
After a pause, Richard's eyes became serious, and he continued to write on the papyrus scroll that served as the experimental codex:
"From the above, the most valuable part of this theory is undoubtedly the use of limit-amplifying hormones. The specific mechanism of action of this hormone on the human body is not clear, but the effect is completely beyond imagination, and only a very small amount is needed to make an ordinary person incarnate into a 'superman', and it is not an exaggeration to call it 'God's blood'.
But how to use it is a huge problem.
First of all, it is difficult to extract, there are many links to overcome, the success rate is not high, the output rate is extremely low, the process is unstable, and the cost is high.
In addition, the source is scarce, and it must be provided with a test product with bloodline seeds, so large-scale production cannot be carried out. In fact, even small-scale production is not possible. At present, only a very small number of laboratory tests can be satisfied, and cannot be used in practice. ”
"Whew-"
Exhaling, Richard stopped writing and thought.
At present, the research on Spartas's heroic potion and bloodline seeds has reached a bottleneck, and the biggest research result, the "blood of the gods", has been confirmed, but it cannot be used.
It's like when you have a hard time guessing the lottery jackpot number, but you can't buy a ticket because you lack two dollars.
So how to solve it?
Richard rubbed his brow vigorously.
How does a hormone like this "blood of God" solve the problem on the modern earth, and how can it be mass-produced?
In the modern region, the most representative case should be...... Insulin.
Well, insulin.
Insulin is a protein hormone secreted by islet β cells in the pancreas, which is the only hormone in the body that lowers blood sugar and is the main drug used for the treatment of diabetes.
As a result, insulin was discovered in 1921 and used in clinical practice in 1922 to treat diabetes, which was a cancer-like terminal disease before the discovery of insulin.
As the times progress, urbanization and longevity increase, the number of people living with diabetes continues to increase – in modern urban living environments, the prevalence of diabetes increases by 68% for every 10 years of age – and as a result, the number of insulin needs has skyrocketed.
Originally, people extracted insulin from animals, such as cows, sheep, pigs, etc. The amino acid sequence and structure of these mammalian insulin molecules are different, with porcine insulin being the closest to human, and people get insulin from pigs to treat diabetes – the first generation of insulin.
However, porcine insulin, that is, the first generation of insulin, is different from human insulin by 1 to 4 amino acids, and it is easy to have immune reactions, subcutaneous fat atrophy or hyperplasia at the injection site, and insulin allergic reactions. Due to its high immunogenicity, it is prone to repeated hyperglycemia and hypoglycemia, and insulin resistance. On top of that, limited by the number of pancreas in live pigs, yields are not very high.
So after decades of research, the second generation of insulin was developed.
The second generation of insulin is a high-purity synthetic human insulin expressed by genetically engineered (recombinant DNA) yeast (brewer's yeast, Pichia pastoris or Hansen's yeast) and recombinant Chinese hamster ovary cells (CHO). Its structure, like the body's own secretion of insulin, eliminates many of the defects of the first generation of insulin. And it can use tissue culture microorganisms, or transgenic animals, for large-scale production, which is widely used to treat patients.
The third generation of insulin was also developed on the basis of the second generation of insulin. Using genetic engineering technology, some structures on the insulin peptide chain are changed to develop insulin analogues that are more suitable for human physiological needs, which can be used during meals, known as prandial insulin or rapid-acting insulin.
Overall, in short, the way to solve this problem on the modern planet is ...... Genetic engineering.
"Genetic engineering. Richard said in a sneer, all thoughts.