"Just go, it's hard to be afraid that the king will not succeed in a little pox!" But the eldest princess and everyone in the family resolutely objected, and knelt down at the door of the study, saying that they were asking for help, but in fact they were blocked and not allowed to go out.

"Daddy is not afraid, but there are still ladies and babies in the house, children can't cure acne rashes, can't protect them thoroughly, and I hope Daddy will think twice." Among these people was Wang Eighteen, and the more she knew about medicine, the more she was afraid of diseases that she could not deal with.

"Get up, this king won't go...... Eighteen, you go and prepare a yard that can be isolated, and Daddy will teach you how to cure acne. ”

After thinking twice, Hong Tao had to give up the attempt to pretend to be a fairy in the village, Wang Shibai was right, he was not afraid, but the family was afraid, in case the virus was brought back, he could only watch them being tortured by illness and having to be buried.

But this situation cannot continue, the pox is indeed not cured, but it can be effectively prevented, and later generations called smallpox vaccination. This method does not mean that it exists, and it needs to be tested for a while.

Whether it can succeed or not, Hong Tao feels that the probability is very high, and it is worth a try. Once successful, it will not benefit thousands of people, but all mankind, and there is great good.

"Daddy, but he wants to wear a pox suit like a Shu doctor? The child tried it in Huangzhou, but the middle one was still not guaranteed, and four or five out of ten died of illness! ”

This time, Wang 18 was not ecstatic, nor was he thirsty for knowledge, and stood still in place. She has done the acne clothing test recorded in ancient books, and the success rate is not high. Just imagine, in the case of a low success rate, who is willing to let the child deliberately get acne rash, and once he dies, he will not play with the doctor.

"This test has also been done? Your tenth sister should be hung on a wooden pole! ”

Hong Tao really didn't expect that Wang Shibai had done everything about the vaccine, and his spirit was commendable, but he couldn't tell where the test raw materials came from. It must still be a child from Wang Shi, otherwise how can I know that the survival rate is low.

“…… It has nothing to do with the tenth sister! It was written incorrectly in the ancient book, and it was effective to soak the clothes with the sick's pox scab grinding powder, and it was effective after wearing it, but it was useless to die of illness or death. "Wang Eighteen doesn't think so, Wang Ten is a great good person to her, and she must protect her with all her life.

"Regardless of whether it is related or not, the father must know what tests will be conducted in the future! Hurry up and clean up the yard, how can the ancients compare the way of the father! ”

Through a simple narrative, Hong Tao probably understood what method Wang Eighteen used, which should be called human pox. It is to use the patient's virus to infect healthy people with diseases, so as to gain immunity.

This method was still used until the Qing Dynasty, but the effect was not as good as cowpox. The reason is very simple, the viral activity of human pox is too great, and after a healthy person is infected with it, it is really similar to having smallpox, and the mortality rate is naturally high.

Although cowpox is also an infectious disease caused by smallpox virus, it is not a smallpox virus, it is not highly contagious to humans, and the symptoms are also mild and less harmful.

Interestingly, as long as a person is infected with the vaccinia virus, he will also produce smallpox antibodies, and he will not be infected with the smallpox virus for the rest of his life. This method is used by human beings to deceive the body's immune system and achieve the goal of completely preventing the smallpox virus.

How to make a cowpox vaccine Hong Tao doesn't know, but he knows where to find the cowpox virus. Since it is smallpox disease of cattle, it is natural to go to the cow to find it.

Then the cattle farmers around Yangzi Town were unlucky, and they would suddenly be visited by King Liang one day, and every cow in the family would be inspected, focusing on the butt and milk. After discovering the herpes, it was closer than seeing my father, and I had to scrub it with warm water, and then use a precious glass bottle to collect the pus inside.

What is the use of these pickles? King Liang's answer frightened the farmer and treated the pox! My mother, what a daring artist! It is said that the female doctor of Liangwangfu can make people have white bones and raw flesh, but I didn't expect that Liangwang is even more powerful, and even acne can be cured.

In view of the fact that King Liang has a history of making Yangzi Town angry, no one doubts the motive of this time, even if there is no cow at home, he will run to tell each other, so that those who have cattle do not wait for King Liang to come to the door in person, and quickly lead the cow to the Liangwang Mansion, which is a great thing to accumulate virtue.

In fact, the people of the Great Song Dynasty do not need to thank King Liang, but should read the good son of an English doctor hundreds of years later, his name is Edward. Chenna.

It was this country doctor who discovered that the milkmaids in the English countryside were usually beautiful, at least without pockmarks on their faces. After careful inquiry, it was discovered that the milkmaid would be infected with a disease on the cow because of her frequent contact with milk, and her hands would be blistered, but she would never be able to avoid smallpox from then on.

After many years of observation, Zener came to the astonishing conclusion that anyone who had been infected with cowpox would not get smallpox again, and the cowpox vaccine was introduced. Since then, smallpox has ceased to be the biggest killer of mankind, and was even completely wiped out in the twentieth century.

Hong Tao thinks that it is not good for Jean Na to be a country doctor, but he has nothing to think about the appearance of the milkmaid, and eighty percent of them are also temperamental, so most of the scientific research results come from interest, even if they are lustful, they can contribute to mankind.

Compared with Chenna, the starting point of himself and Wang Eighteen is much higher, and he belongs to standing on the shoulders of giants, and there is no reason why he can't get a cowpox vaccine. Think about it, in a few hundred years, your name will be admired by the world, and the bitterness of touching the butt and milk all day long is not worth mentioning.

Not only did he touch, but also mobilized the whole family to touch it together, whoever touched the herpes on his hand would be rewarded with half a year's regular money, and whoever didn't touch it would be dealt with by family law!

This time the cow was unlucky again, and the people didn't believe it just when they heard that the herpes on the cow could prevent pox, but when they saw that King Liang brought the whole house to touch it, they immediately believed it. What is the identity of King Liang? The eldest princess is more noble, and everyone has touched our people, is it a matter?

Cattle raisers look at it, but they can't let people come to the house every day to touch it, even if people are happy with the cows. So there are people who specialize in selling the opportunity to touch the sick cow, one penny at a time, and the child is not bullied, and there is not enough herpes on the milk to be embarrassed to pull it out.

With Dr. Turner as his guiding light, Hong Tao's cowpox test was not only smooth but also fast. Dr. Zener was groping in the dark, unable to find a healthy child for testing, and it took years to prove an idea.

Hong Tao is according to the map, you can also go to Yangzhou City to buy a child who has not had smallpox to come back to test, even if the experiment fails and dies, at most it is to pay a fine to the government, and the lives of the poor are not worth much.

In less than a month, Wang 18 completed the test of vaccinia, observing a sample of ten children, all of whom were three years old, five boys and five girls.

If Dr. Zinner had a spirit in heaven, he would have to come down and play with Hong Tao. Plagiarism and plagiarism are so high-end and atmospheric, so that the original work will not be lived!

All 10 children had fever after being vaccinated with cowpox, and some also had a small area of herpes, which would be cured in about a week, and none of them died.

The next step is to vaccinate these ten children against the human smallpox virus, if no one gets sick, it means that the vaccinia really works, and it can basically be determined that the safety of vaccinia can be used for clinical popularization.

As for whether this kind of clinical trial is scientific or not, Hong Tao does not consider it at all, even if the mortality rate reaches 1 in 10, it is a miracle drug. exchanging the life of one child for the health of the other nine children, even if this kind of lawsuit reaches the emperor, Hong Tao dares to confront anyone.

Before infecting the ten children with the smallpox virus, Hong Tao personally cooked a pony dish for them, as well as cream cakes from the kosher bakery, which he could eat in unlimited quantities.

Even if they know that cowpox must work, this kind of experiment is still life-threatening, and the condemned prisoners are given a meal of wine and meat to eat before the execution, not to mention these ignorant children who don't know what is going on, but have a fear for their lives.

This is what they deserve, and Hong Tao can only do this. Kindness is all prefixed in his mind, and even if the eldest princess begs many times to let these children go, she will not be soft-hearted.

"Officials, officials, come out quickly, Lord Shen Cunzhong is here!" Seeing that the children had finished eating a table of dishes and three large cakes, and Wang 18 had also prepared the vaccination equipment, Wang San's shout suddenly came from outside the courtyard gate.

"Oops, eighteen, hurry up and help Daddy change his clothes and disinfect them, a distinguished guest has come to the house!" If someone else came to visit, Hong Tao would definitely make him wait.

This small courtyard has become a forbidden area, and there is a cordon with white ash outside, except for Hong Tao and Wang Shibai, there are two special forces who have smallpox who are responsible for taking care of the children's daily life, and no one is allowed to approach. Every time I go in and out, I have to disinfect and change clothes, and the trouble is dead.