499 [Discovery]
In the next half month, Zhou Hexuan took Guo Taiqi around to visit British celebrities, and he was also carrying out his real estate business.
First of all, Zhou Hexuan bought a villa in the suburbs of London as his and Vivien Leigh's exotic love nest. Immediately afterwards, Zhou Hexuan bought several factories north of Hampton Court Palace, and even packaged and purchased all the factories with machines and land.
The factory was located in what would become London's Busch Park (the second largest royal park in the UK), but it was still an industrial area. It is full of factories of all sizes, and due to the global economic crisis, 20 percent of the factories in the area are in a state of shutdown, and 30 percent of the factories are in a state of semi-shutdown.
There are three main reasons why Zhou Hexuan chose to buy land here: first, it is close to the Thames River and has convenient transportation; Second, the price of industrial land has plummeted and is very cheap; Thirdly, the location is in the west of London, and the German bombing will not affect it in the future.
At this moment, there was good news from University College London.
Aldrich and his students analyzed the active ingredients of "Bailang Duoxi" and decomposed a substance called "amenylsulfonamide". (Lao Wang doesn't understand medicine, so he confused Bailang Duoxi with sulfonamide, and aminosulfonamide is still very easy to find.) Sorry that the content of the previous section has been modified. )
"Viplamide" is "sulfonamide" in the traditional sense, which is an antibacterial substance generated in the body after taking "Bailang Duoxi". Moreover, it is also an intermediate of other sulfonamides, and if someone wants to develop more advanced sulfonamides in the future, they must use "triamsulfonamide" to make it.
In other words, as long as Zhou Hexuan applied for a patent for "sulfonamide", he would choke the neck of all sulfonamides.
Aldrich pointed to the powder in the glass dish and said excitedly: "Zhou, it is this substance that can kill streptococcus." After taking Bailang Duoxi, the mouse will form a bactericidal substance in the body. We were lucky enough to find it after only five experiments, and I call it sulfamelamide. Amsulfamine can also kill other bacteria, as long as the powder is applied to the surface of the wound, it can effectively inhibit the growth of bacteria. ”
Zhou Hexuan asked: "Can sulfaminyl be produced on a large scale?" ”
"It should be fine," Aldrich said after a moment's thought, "the structure of sulfamsulfonamide is not complicated, and it can be easily synthesized in the laboratory." As for the method of large-scale production, we still need to continue to explore. I believe that it will not be long before a new drug that 'cures all diseases' will be born. ”
"Then please," Zhou Hexuan said happily, "You prepare the relevant materials, and I will apply for a patent." ”
Aldrich reminded: "You'd better go to the president of University College London first, I can help you introduce it, and you can apply for a patent with the help of the school." ”
Zhou Hexuan was dizzy: "What does this have to do with the University of London?" ”
"Of course it does." Aldrich smiled and began to explain.
It turned out that applying for a patent for a drug in the UK at this time was complicated and had to be supported by the relevant authorities. One of the most authoritative institutions is called the "Medical Research Council of the United Kingdom (MRC)", in addition to this, there is also support from universities such as Cambridge, Oxford, and London.
Without the accreditation of these authorities, the UK Patent Office would not have granted it. Historically, penicillin was not recognized by the MRC and Oxford University, so it could not be patented in the United Kingdom, and finally had to go to the United States to develop.
Fortunately, Zhou Hexuan was rich, he directly donated 10,000 pounds to the University of London, and with his fame and the actual bactericidal effect of sulfaminamide, he soon won the institutional support of the University of London.
Zhou Hexuan can only sigh about this, the Chinese in these years are really difficult, and even applying for a patent is so difficult.
First of all, you must have the money to buy a house in the UK, or start a company and set up a factory. Secondly, you have to convince the authorities to approve it, and these institutions are so bureaucratic that they won't open their eyes without any benefit – even penicillin will be shut out.
It's a little more convenient in the U.S., but you also have to have a real estate. This is an explicit provision of the Paris Convention, and people who are not members of the Paris Convention must have a fixed property in order to apply for a patent.
In other words, a foreign student in the Republic of China with excellent grades, even if you have made major research discoveries, if you don't have the money to buy a house abroad, you will at most publish a few papers to gain fame, and you will not even be qualified to apply for a patent.
After Zhou Hexuan obtained the support of the University of London, the patent office was very efficient, and the patent right of aminobenzenesulfonamide was granted in a few days.
Zhou Hexuan immediately took the patent certificate and ran to Albert: "Your Royal Highness, I have something good for you to see." ”
"Specialized...... Patent? Albert was puzzled.
"Yes, the patent, the patent for a miracle drug," Zhou explained, "This drug is called sulfonamides, it was discovered by a professor at the University of London, and I now own his patent rights." ”
Albert still didn't figure out the situation: "Why did you let ...... Let me see these? ”
Zhou Hexuan said: "Nowadays, the postoperative infection rate of surgery is very high. Even if the operation is successful, many patients have a high chance of dying from bacterial infection, and sulfonamide can effectively inhibit the growth of bacteria, greatly improving the survival rate of surgery. This drug can save countless lives and even have a chance to win the Nobel Prize in Medicine. ”
"So...... Magical? Albert was finally a little surprised.
Zhou Hexuan said with a smile: "I am going to invest in the construction of a factory in London to manufacture this new drug, and I hope that His Royal Highness the Prince can become a shareholder." ”
"Why are you looking for me?" Albert couldn't figure it out.
Zhou Hexuan said truthfully: "I am Chinese, and it is likely to be difficult to set up a factory in the UK, and with the participation of His Royal Highness the Prince, it will definitely be unimpeded." ”
Albert smiled: "Don't worry, Britain is...... It is a country that abides by the rules of business and will not be ...... Make it difficult for you. ”
Zhou Hexuan said: "Please be sure to buy shares." ”
Albert didn't care about it: "Okay, I'll vote...... Invest £1000. ”
"Then I'll give you 10% of the shares," Zhou Hexuan said with a wink, "Your Royal Highness, this is a super good deal." ”
"Perhaps." Albert said he didn't care about the money.
Zhou Hexuan soon found Vivien Leigh's father again, and as a once successful businessman, Ernis quickly realized the great value. He promised to dispose of his factory as soon as possible, invest 8,000 pounds in exchange for a 15% stake in the pharmaceutical factory, and take charge of the operation and management of the factory.
Throwing out 25% of the shares at once, Zhou Hexuan didn't feel pain.
Partner, if you don't give more benefits, why should you ask others to do their best?
British society was quite conservative at this time, countless times more conservative than the United States and France. It is difficult for Chinese to do business in the UK, Prince Albert is equivalent to an umbrella, and Ernis is equivalent to a spokesperson.
As for why the pharmaceutical factory was built in the UK?
Zhou Hexuan is also very helpless.
If you think about the fate of the founder of Yunnan Baiyao, you can see how terrible it is to build a sulfonamide factory in China, which will be swallowed up by those in power sooner or later, and China's chemical base will not be able to support the production of sulfonamides.