The auctioneer obviously doesn't think that this beautiful girl really has the ability to buy the Old Summer Palace, and the Grand Duke and the Great Scientist won't let this little guy go, right? He looked at Downing with a smile on his face, as if he were watching his joke.

At this time, Qi Taiyu, a big comprador who hadn't decided what to buy, roared: "Grand Duke, buy the Old Summer Palace, what are you afraid of?" Are you not afraid of the United States, Russia, and France, but are you afraid of buying the Old Summer Palace? Isn't it just a garden? Let's get it! ”

A bunch of foreign adventurers heckled and shouted, "deal! deal！ deal！ ”

Xu Rongcun and Xu Run are both Cantonese, and deal is very much like a swear word in Cantonese, which makes them laugh.

Oh, it's hard to be gracious! However, Tang Ning had one last trick and said to everyone: "If the Italians have to choose me as king, then I will find a palace in China, and the Old Summer Palace is good." ”

When Chinese and foreign adventurers heard this, the atmosphere reached ****, and the whistle sounded everywhere. Mazzini was trying to promote a republic, and Downing would not interfere with him, presumably with Mazzini's current prestige in Italy, he should get what he wanted.

However, after the surrender, Cavour struggled to promote a constitutional monarchy, and it is difficult to say that this proposal will become a dark horse. Led by the former kings of Sardinia and the two Sicilies, who advocated federalism and wanted to win some privileges for their families in the convincing states, they could also support Downing's accession to the throne as king of Italy, leaving a little room for their own privileges.

The naughty little girl's cry disrupted Downing's original plan, and it was really possible for him to ascend the throne as king of Italy. Could it be that he would really buy the Old Summer Palace, which represented the dignity of the Qing Dynasty? It's a real headache.

Now, Princess Louise really admires her best friend to the extreme, and the little princess herself is a troublemaker, which gives the queen and the prince a headache, and now it seems that she is a little witch.

At this time, the security assistant flew over and handed over a telegram, and Downing took it: "The East India Company Navy clashed with a U.S. Federal Navy warship at Pearl Harbor, Hawaii, and there were casualties on both sides in the shelling. Exploration troops request reinforcements. ”

The incident was reported at a later news time, and it was stated that the United States of America would pay the price. The American Union was overjoyed that it had finally found a reliable ally, and this time the East India Company would no longer be as lip-professed as the French, and the President of the Confederate States of America, Davis, immediately summoned the head of the local Reuters news agency to express to him the desire of the Confederate States to establish a strategic partnership with Luxembourg.

In order to stabilize the New York stock market, Lincoln persuaded Russia and France to ask the three countries to make their alliance open, and held an ambassadorial-level meeting in Paris to establish the "North Atlantic Treaty Organization", with Prussia as the "observer" of the organization, and the purpose of the organization was to "break the industrial monopoly of the Windsor consortium". NATO said that the Windsor consortium's monopoly on telegraph, electricity, oil, antibacterial drugs and other fields has seriously threatened the fairness of world trade, and the United States, Russia, France and other countries have called on the world to boycott this monopoly and recreate a level playing field for world trade.

How? NATO did not say it, but the three countries are taking military action, presumably trying to rob it. The U.S. ** ship swooped down on the headquarters of the Panama Canal Company with great momentum, France invaded Italy and the port of Windsor, and Russia continued to send troops to the Far East to prepare for the invasion of Japan, a friend of the Windsor consortium.

The establishment of NATO, however, greatly affected the shares of the Windsor consortium. In particular, it seems that the Windsor consortium could not find a foreign power to back, and only Britain waited to see what happened, and the British government told The Times that it had not received a request for help from the Duke of London.

The French finally passed the news of the abduction of the Qing Emperor to enough people, the Hunan army, Shi Dakai, who still had 20,000 troops in Guangxi, the twisted bandits who raged in Huaibei, and the monk Greenqin, who returned to his hometown to retire, and the Jianrui battalion of the Eight Banners who was dismissed. Sichuan, Guizhou, and other places have self-financed military training, and with the unremitting efforts of the French, these local forces that may not obey the imperial court are playing their own small calculations. However, for the time being, no one dares to be the first bird, just kidding, the Taiping Army was so arrogant that it was wiped out by the British army, and no one dared to underestimate the strength of the Windsor Consortium. What is the attitude of the UK towards the Windsor consortium now, no one is sure.

The attitude of the British government, more ****, of course they don't want the guy with the big name for the Duke of London to be bullied, but they are eager to reap greater benefits, especially when the Duke of London has obtained almost all of Italy, as a head of state, the gap between the Duke of London and the United Kingdom is even greater. Palmerston was eager to take back control of India, and if Downing came to the British government, he would have a chance. India grew rapidly under the conditions of a Downing-dominated free-market economy, and the East India Company was said to have broken even, and how honorable it was to rule over 300 million subjects in such a situation that Palmerston could not sit still.

The British peddlers called for the Duke of London to bring down Washington every day, because their trade with the American South was blocked by the Union Army, especially the Manchester textile industry, which relied on cotton, and a large number of unemployed workers pinned their hopes on the Duke of London.

In this case, Downing returned to London, and the small traders cheered, they thought that Downing had come to London to discuss cooperation with the British government, but Downing only came back at the request of the little princess to see Albert's stomach disease, he had already said that he didn't know how to cure stomach problems at all, but he couldn't bear Louise's soft words and begged, and he had to go back to London, he had never been able to stand the coquettishness of the little beauty, you know.

"This is the Prince's gastroscopy photo? It's not like a normal stomach ulcer. Tang Ning looked stern and very helpless, he didn't know how to look at stomach lesions at all, even if he led the invention of the gastroscope, it was useless. His words really disappointed everyone, and the prince, the queen, and the little princess and the little prince were all stricter.

In order to study the Prince's condition, Tang Ning had recently discussed a lot with the ace physician at Windsor Hospital, and suddenly, an ominous premonition surged in his mind: it would not be ...... Stomach cancer, right?

Cancer is also called tumor, some tumors are indeed a big bag, but not all cancers are so obvious, otherwise the surgeon only needs to remove the tumor, but many cancers are moisturizing and silent, and the appearance is exactly the same as normal cells.

The essential difference between cancer cells and normal cells is that they divide out of control, so a sample of diseased cells can be diagnosed by taking a sample of the diseased cells for in vitro culture observation.

The specific characteristics of the split out of control are as follows:

1. Under suitable conditions, cancer cells can multiply indefinitely and become "immortal" immortal cells. Normal cells have a certain maximum number of divisions, such as human cells can only divide 50~60 times in a lifetime. However, cancer cells lose their highest number of divisions. This phenomenon can be observed, but it takes too long to diagnose cancer.

Second, after normal cell growth comes into contact with each other, its movement and division activities must be stopped. Under the condition of in vitro culture, the surface xiàn is the adherent growth of cells, and the growth stops after confluence into a monolayer. Cancer cells are different, their division and proliferation are not terminated by contact with each other, and cells can accumulate into somatic cell populations when cultured in vitro, so cancer cell contact does not inhibit the proliferation of cancer cells. The trick to in vitro culture is to use a culture medium containing about 10% serum.

3. Compared with their homologous normal tissues, cancer cells have reduced adhesion between cells, so cancer cells are easy to disperse and metastasize in the body. Fibronectin in the normal extracellular coat is an extracellular adhesion glycoprotein that enhances the adhesion between cells and the extracellular matrix. Fibronectin in cancer cells is significantly reduced or absent, and cadherin synthesis is impaired, thus disrupting the adhesion between cells and the stroma and between cells, so cancer cells have the property of easily infiltrating tissues and metastasizing.

Fourth, cancer cells are more likely to be agglutinated by lectins than normal cells, so the concentration of lectins required to cause agglutination of cancer cells is much lower than that of normal cells. The increased agglutination of cancer cells is due to profound changes in the structure of the plasma membrane. Glycoproteins are more motile in the plasma membrane, making it easier for lectins to cluster their receptors (glycoproteins) to form more transverse bridges. The increased motility of plasma membrane glycoproteins may also be due to disruption of the microfilaments attached to them.

5. In vitro culture, cells grow adherently, which is related to the secretion of glucosaminoglycan viscous substances by cells. Glucosaminol is the main component of the extracellular matrix, which forms a hydrated gel. The synthesis of glucosaminan by cancer cells is reduced, and the mucous properties of cells are reduced.

6. Normal cells can only grow in vitro in a culture medium containing more than 10% serum, which contains some growth factors required for cell growth, such as epidermal growth factor (PGF), platelet-derived growth factor (PGDF), insulin, etc. Transformed cells, on the other hand, can be grown in culture medium with very low serum concentrations, and the need for growth factors is greatly reduced.

Through the observation of five phenomena, including the loss of contact inhibition of cells cultured in vitro, the weakening of adhesion between cancer cells, the ease of agglutinin agglutination, the decrease of stickiness, and the decrease in the need for growth factors, the diagnosis of cell carcinogenesis can be confirmed, and the number of divisions is out of control can be used as the final confirmation. （http:／/.）。

After a series of thoughts, Tang Ning began to organize a research team to conduct in vitro culture of the prince's stomach cells, and collected the stomach cells of a number of healthy volunteers as a comparison.

The scale of the research team he organized this time was huge, and the number of direct participants exceeded 100 people, which scared the prince, and after asking, he learned that Tang Ning suspected that he had cancer, which was the king of diseases, which was quite not optimistic. The reason why cancer is king has something to do with its ability to effectively break through the human immune system. If cancer cells do not have lesions, they are very similar to normal cells, and when lesions occur, cancer cells have accumulated to the scale of 1 billion. (There are a total of 10 trillion levels of adult body cells). Once it reaches the level of 1 billion cells, it already has a certain ability to mutate to adapt to the new environment, providing a good number base for further expansion and transfer.

For example, gastric cancer cells are originally cells of the stomach, and they need to mutate again in order to break through the adaptation of gastric cells to the new living environment, and the chance of success of this mutation is 1 in 100 million. This is why the earlier the cancer occurs, the higher the probability of cure, and not all cancers have a chance of successfully metastasizing.