Chapter 0286 Genetic Testing

The next day, Wei Danian was completely out of danger.

The blood pH value returned to the normal range of 7.40, the blood lactate also decreased to the normal range of 1.0 mmoll, and the other electrolytes potassium, sodium and calcium chloride returned to the normal range.

As long as the acid-base imbalance and electrolyte imbalance are corrected, and the patient regains a stable internal environment, life is out of danger.

The internal environment of human cells, just like the living environment of human beings, must be maintained within certain parameters, otherwise survival will be threatened.

Wei Danian's tracheal intubation was successfully removed, but for safety reasons, he still needed to be monitored in the ICU for one day before he could be transferred to the general ward.

In the ICU ward, all the patients lying down were seriously ill and critically ill, and there were patients who could not be rescued at any time, Wei Danian could only lie on the bed, and his body was still connected to various pipe lines, and he was naturally afraid in his heart, he shouted to be discharged, shouting.

The doctors and nurses kept persuading the twenty-five-year-old man, like a child, not to be relenting, and there was no way, so Dr. An contacted Dr. Kim to prepare to transfer to the trauma orthopedic department.

But before the phone hung up, Wei Danian fell asleep again, snoring like thunder, snoring for a while, suddenly, there was no movement, the ECG monitor actually showed that breathing stopped, Dr. An quickly approached his nose to listen to breathing, really breathing stopped, a moment, Wei Danian opened his eyes, looked at a few times in a daze, snored like thunder, and breathed again.

Obstructive sleep apnea-hypopnea syndrome, which is common in obese men, often at night due to the collapse of the upper airway obstruction, resulting in apnea, and then the patient wakes up and breathes again.

"After transferring to the orthopedic department, it is recommended to consult the respiratory department for sleep apnea monitoring." Dr. Ann instructed the trainees beside him.

Dr. Jin asked Wei Danian's parents in detail about the number of episodes and specific months of the year and drew a statistical chart, according to the statistical rules expressed in the statistical chart, there will be no seizures for the time being.

Before finding the inner law, this kind of appearance law can also play a role in predicting, at least to guide the patient which season and month of the year is the most dangerous.

Dr. Jin will report the results of Wei Danian's examination once a day in the group, so that everyone can analyze and discuss how to check next.

Blood sugar is very well controlled, elevated blood lactate caused by diabetes can be ruled out, according to the results of the examination, acquired diseases are also ruled out one by one, everyone will focus on hereditary diseases, although it has been checked in other hospitals, but it is necessary to check again.

Wei Danian's parents agreed to track down the cause, the dead horse became a live horse doctor, the doctor's enthusiasm was so high, of course they were willing to cooperate, just such an only child, every day worrying, if the cause can be identified, the cause can be treated, maybe this tight spell can be lifted.

"Can I contact the genetic laboratory of Nandu Medical University for gene sequencing?" Yang Ping suggested Dr. Kim.

When considering hereditary diseases, genetic sequencing is performed to find the cause at the genetic level, as well as to investigate the family history and map the family lineage.

"Contact the Genetic Laboratory of Southern Metropolis Medical University? It's a bit difficult! Dr. King responded.

"I'll get in touch!" Yang Ping responded.

"There is a problem with pyruvate conversion, an enzyme defect or an abnormal mitochondrial function in the base camp where lactic acid is processed, which can only be figured out by genetic sequencing." Yang Ping analyzed.

"Congenital lactic acidosis, which is a deficiency in the enzyme structure or activity of pyruvate conversion, was first reported by Hartmann et al. in 1962, transmitted in the form of X-accompanied inheritance, and its mutated gene is on Xpz, patients generally have retardation of intelligence and motor function, and have hepatomegaly, heart enlargement, cataracts, etc., it is recommended to test intelligence with an intelligence test scale to assess motor function, it is very strange that this patient does not have a large liver, no cataracts, and the size of the heart also matches the body type." Endocrinology is a doctor's opinion.

Yang Ping contacted Su Nanchen on WeChat, explained his thoughts, and sent him the case, Su Nanchen was very interested, and immediately recommended Wen Yulin, a young female doctor in the genetic laboratory of Nandu Medical University, ---.

The efficiency of the Internet era is high, and soon, Su Nanchen and Dr. Wen were pulled into the group, and Dr. Jin re-posted Wei Danian's information so that they could see it, and also sent a screenshot of the discussion just now to the group, so that they could understand the progress of the discussion.

Dr. Wen was very interested in the case and quickly responded: "Our lab can test gene fragments, and we can detect whether there is a mutation in Xpz. ”

"How are specimens collected and stored, and does ethical approval be required?" Also, how much does it cost? ”

The discussion speeches in the group began to swipe the screen like snowflakes, and the discussion has been upgraded from clinical to genetic testing, and everyone is extremely excited.

This is a challenging collaboration, where clinicians and researchers in basic medicine rarely intersect, and doctors may also deal with basic medical researchers when they study for graduate studies.

"I'll send you a detailed standard collection and ethics process later--- Dr. Wen is very positive.

From the clinical symptoms of a patient, it gradually deepened into the level of genetic testing, and all kinds of knowledge that is usually isolated are connected.

This is not destined to be an ordinary case, Yang Ping faintly feels that this case will create a new diagnostic model, and it is very likely to find an unknown disease.

Because, none of the existing known diseases can match Wei Danian's condition.

Medicine needs this group of passionate and courageous people to challenge the unknown, without paranoia, without madness, and it is difficult to move forward on the road of overcoming obstacles.

Approaching the Spring Festival, the festive atmosphere is getting stronger and stronger, and the hospital has begun to hang red lanterns in advance.

Usually at this time, everyone is discussing the Spring Festival holiday or grabbing tickets, but the doctors and nurses are very calm, because everyone has not taken a vacation, and there is no such thing.

Zhang Lin discharged the duty schedule for everyone to see, there was no special matter, and the Spring Festival was implemented according to this schedule.

---

Luo Jin participated in the recording of the hospital's promotional video, and also participated in the recording of a comprehensive orthopedic documentary, and the TV station specially added an episode to him to record his injury, surgery and recovery.

Hermes was discharged from the hospital, he went to the outpatient clinic to continue treatment, the emaciated camel was bigger than a horse, he sold a house near the hospital, a duplex house of more than 200 square meters, and got more than 10 million cash after selling.

This guy is very financially savvy, he used cash to buy another 140 square meters of house near the hospital for himself to live in, and the remaining 4 million cash, he went to Nandu High-speed Railway Station to buy a small investment house, and finally held 1 million cash in his hand, which he used to treat his illness and look for opportunities to make a comeback.

In this way, although the house has become smaller, the house is still there, the cash is also available, and there is a small house that can appreciate in value.

During the hospitalization of Hermes, it was the peak of the price increase in the community next to the hospital, but I didn't expect that now as soon as I made a move, I not only earned back the medical expenses, but also earned a handful.

Luckily, Hermes just went bankrupt, and other worries, such as jail time, didn't happen for the time being.

I just heard that he was bankrupt and at risk of prison, and those relatives and friends had lost contact with Hermès, including relatives who were often helped by Hermès.

The rich live in the mountains and have distant relatives, and the poor live in the downtown and no one asks.

In the past, although he went to G City to seek medical treatment, his relatives and friends kept calling him for condolences, and he sometimes had heart-warming messages on WeChat, and people often sent various precious medicinal materials to the hospital.

Now, overnight, it seems that the mobile phone is disconnected, there are no calls at all, surprisingly quiet, occasionally Hermes wants to inquire about the news, call relatives and friends, send WeChat, but there is no response, and some simply block it.

After this change, the eldest brother went to the oncology department again, and his understanding of life was more profound, and he no longer struggled with the huge gap, and faced life calmly.

As Yang Ping told him: "If there is no obvious abnormality on your checklist, it is your greatest happiness." ”

Hermes bought a good set of stereos, and every day he had nothing to do with his wife to push his wife to the overpass next to the hospital, and sang an old song "Sea and Sky" with his throat.

Passers-by all burst into tears, and although there was no pot in front of him to beg for money, a kind passer-by still generously donated money and threw a dollar or ten yuan of change in front of him.

But they were all picked up by Hermes and handed back to passers-by, and the eldest brother sang, nothing more than to find a place to be comfortable, although he was down, but he was not bad for this money.

With the cash from selling the house in hand, and entering and exiting the stock market on your mobile phone every day, you can also earn money to support your family, and the mind to invest is also a survival skill at this time.

Sisi's surgery entered the third stage, dealing with tumors in the lungs, which were very difficult to focus on high-frequency ultrasound because of the obstruction of the ribs, and the ultrasound could only pass through the narrow space between the ribs.

However, Yang Ping has repeatedly simulated in the system space and obtained accurate data, which can be used to complete the operation.

Medicine, Iron and Fire! The energy represented by fire will surely shine in the future.

Perhaps one day, many surgical procedures will not even require small incisions that are minimally invasive, and the energy will be able to remove the lesion.

It will be a new era.