Chapter 0355: Old Tie
Yang Ping's choice of stem cell muscle cultivation as a topic was not a whim, but a deliberate one.
If successful, it is easier to overgrow other organs, such as skin, tendons, ligaments, cartilage, bones, and even joints.
In the long run, it can also develop towards cultivating the heart, liver, kidneys, etc.
It is also relatively convenient to organize technology and equipment for this project, such as nano-micro scaffolds, which are relatively easy to obtain through Takahashi.
Nano-microscaffolds have very high requirements for 3D printing technology, and their three-dimensional structural arrangement is at the level of cell clusters, which should be able to guide muscle fibers to carry out spatial configuration.
This level of 3D printing technology is currently not available in China, and the core technology is monopolized by German and Japanese companies.
This is also the reason why Yang Ping seeks international cooperation, it is impossible for one person to break through all industrial technologies, and he can only work medical technology.
The obstacle that the United States and Japan cannot overcome now is the collapse of cells, which stems from the instability of certain cell structures, and there are many factors of instability, which may be the instability of cell membranes, but also the instability of organelles.
Many of the papers now hypothesize that these collapse factors, any one of which acts as a triggering factor, causes the cell to collapse, causing other structures to collapse with it. It is not surprising that researchers focus on one side for various reasons when making observations.
This is the inevitable result of artificially induced stem cell differentiation, and in the case of immature induction technology, it is bound to cause partial structural instability, which is the potential cause of collapse.
In fact, the cultivation of stem cells in organs has been in full swing.
The University of Tokyo also cultivated the world's first heart, 1 mm in diameter, with complete ventricular and atrial vascular structures, about the size of a mouse fetal heart.
The National Center for Adult Education Medicine, also in Japan, cultivated the liver; The University of Edinburgh in the United Kingdom cultivated kidneys; Harvard University in the United States cultivated skin.
These technologies all face a common problem – maturity and stability.
If this problem is solved, these technologies will be able to move from the laboratory to the clinic.
Muscle culture is still the most mature and can be transplanted into animals for a few weeks to survive.
Those internal organs, such as the heart, a small heart with a diameter of only one millimeter, are cultivated upwards, and they face the problem of collapse, and they cannot make the small heart grow smoothly.
Yang Ping wants to start with muscles and solve the problem of maturity and stability.
Then it expands to the skin, tendons, cartilage, etc., which are widely used in orthopedics.
With skin, there is no need to tear down the east wall to make up the west wall for skin grafting or skin flaps.
With tendons, those patients with ligament reconstruction will have better surgical outcomes.
With cartilage, it is possible to address degenerative diseases of cartilage, such as senile knee osteoarthritis.
Even a joint was cultivated and a joint was replaced.
Stem cells are the most promising field of surgery in the future that will change the history of surgery.
Perhaps one day, a patient like Yu Shuilian can use her own cells to grow a complete lower body, and then undergo transplant surgery to connect the upper and lower body to restore a complete body.
After work in the afternoon, the young doctors of the comprehensive orthopedic department, whenever they are free, go to Mr. Guo's dinner.
Mr. Guo was generous and set up several tables in the Hakka restaurant next to the hospital, how happy he was to be willing to bleed so much.
After eating and resting for a while, Xiao Su said that Fujiwara Miyuki asked her to play ball with her, and asked Yang Ping to go with her.
They seem to have made an appointment a long time ago, with tennis suits under their jackets and backpacks for rackets.
Xiao Su usually works in the comprehensive orthopedic operating room, but he only deals with Miyuki when he is doing surgery, but he didn't expect them to chat well, and Tang Fei, the three of them seem to be old friends.
Everyone rests for half an hour, then goes to the court and so on, and can almost do strenuous exercise.
Song Zimo, Tang Fei and Xu Zhiliang returned to the department, Xiao Wu wanted to go home to accompany his wife, Zhang Lin's wife was on duty, he made a few bags, all of which were his wife's favorite food, and he had to send them over in time.
Yang Ping, Takahashi, Kosu, and Miyuki went to play tennis, but Yang Ping and Takahashi did not change their clothes.
Xiao Su pulled Yang Ping: "I'll have a good game with Miyuki, just be the audience." ”
Miyuki held Xiao Su's hand again: "China-Japan women's tennis friendly match." ”
Takahashi felt as if he had become superfluous, following behind, keeping a certain distance.
However, watching two tall beauties play tennis is actually quite eye-catching.
The two of them even booked the venue of the hospital gymnasium in advance, and Yang Ping and Takahashi simply sat down next to them to discuss the matter of project cooperation.
The two stunning beauties played tennis, which attracted a lot of attention from the side, and people looked at them from time to time.
Both of them are at a very good level, very intense, the fight is not a winner, the score is very tight, it seems that Xiao Su has met an evenly matched opponent.
Takahashi took the initiative to propose: "Dr. Yang, the premature collapse of cells is a problem faced by all stem cell cultivation organs at present, if it can be solved, this is epoch-making progress, if Dr. Yang decides to set up this topic, Takahashi asks for cooperation, the research group of the University of Tokyo, I am the main person in charge, and I have enough right to speak." ”
"Collaboration saves us a lot of time, and I don't want to reinvent the wheel, I just want to tackle the most critical difficulties." Yang Ping expressed his intentions.
"If Dr. Yang is willing to cooperate with us, we can share all the early technology, which saves Dr. Yang's time, and we are a win-win situation." Takahashi thought the same way.
At present, the University of Tokyo is at the forefront of this technology, but it has encountered difficulties, and Yang Ping analyzed all the current papers.
It was found that recent papers at the University of Tokyo all focused on the survival period of cells implanted in animals, and the increase in extended time, one or two days, was very slow.
It shows that they have no technological breakthrough for the time being, but they are just constantly improving the original technology.
Working with them will give you more results with less.
Scientific research is similar to navigation, and the opening up of a new route requires countless trials and errors, continuous corrections, and accumulation of data.
If you get the artifact of the system space laboratory in the future, you will also need a real laboratory to complete the experiment.
The data obtained in the system space laboratory can allow you to avoid detours in reality, or even achieve it in one step, but you also need the real laboratory to repeat the entire experiment.
Therefore, it is beneficial and harmless to cooperate with these top international universities or hospitals.
The key is how to use and control these resources, to be the leader in them, and to insist on self-reliance and renewal of scientific research, but also to open up and cooperate, Yang Ping thought.
Takahashi had seen Yang Ping's surgical skills and thinking ability with his own eyes, and he was convinced of Yang Ping's ability.
Now because of the friendship established with Yang Ping because of further study, he is close to the water and has the honor to cooperate with him.
In the future, when Yang Ping's scientific research becomes a climate, it is estimated that the team cooperating with Yang Ping will have to queue up, and it will be even more difficult for Takahashi to squeeze in.
Yang Ping watched the beauties play, and thought: "Takahashi, then we will cooperate and share the results." ”
"No problem, I will send a formal email to the University of Tokyo in the evening to obtain authorization to negotiate and sign the contract, we will definitely not be worse than Duke University, although we use stem cells to grow muscles later than them, but we also completed it independently, but the paper was published a little later, compared to them, we are more advanced in induction technology and microscaffolds, their animal survival time in vivo is three weeks, we are six weeks."
Since Takahashi met Yang Ping, he has constantly seen Yang Ping create miracles, and he firmly believes that if Yang Ping focuses on the field of stem cells, he will definitely be able to create miracles.
From a selfish point of view, Takahashi wants to take this tailwind ship, as for the conditions of the laboratory, the existing technology, for others, it may be very precious, but for a person like Yang Ping, even if you don't cooperate with him, he himself can catch up, it's just a little longer.
At that time, if he proposed cooperation, it is estimated that Yang Ping was not interested at all, and now that he proposes cooperation, at least he can use the existing technology to help him save time.
After playing a few rounds, the two beauties are drinking water, talking and laughing across the net, both of them are sweating, and the girls in sports are really cute.
After five rounds, Xiao Su was a little better and won three games.
Everyone packed up their things, Xiao Su and Meixue went back to the dormitory to take a shower and change clothes, Yang Ping and Gao Qiao went to occupy a place, and a few people wanted to find a barbecue stall to eat supper.
Yang Ping called Song Zimo, Xu Zhiliang, Zhang Lin, and Xiao Wu out.
Zhang Lin is still in the pediatric department, accompanying his wife on the night shift, Xiao Wu's home is near the hospital, and the two will be there soon.
Song Zimo and Xu Zhiliang were peeling grapes under the practice microscope, and when they heard that there was a supper to eat, they did not hesitate to come out.
Everyone gathered around, Zhang Lin asked for a few boxes of beer, except for Yang Ping and Song Zimo, who didn't drink it, all the other men drank it.
Several big men opened their mouths and continued the topic just now, and Song Zimo and Xu Zhiliang also joined.
The three girls chatted together, Fujiwara Miyuki Chinese is very good, from time to time burst out interesting Internet terms, making everyone laugh, but also hugging Xiao Su and Tang Fei to take selfies and send moments.
Takahashi drinks very happily, as soon as the cup is touched, it will be dried up immediately, and in strict accordance with Mr. Tang's explanation, no matter who you clink glasses with, the cup must be lowered by one centimeter.
"When I go to Japan, I invite you to drink Marina beer from Wakayama!"
Takahashi felt that these Chinese friends were really good, and he wanted to learn from Abe Nakamaro and write an article on this training, preferably a book, so that the Japanese could also have a long insight.
The girls didn't know what to talk about so happily, as if they were talking about what was fun in China, and Miyuki had found a good sister in China.
They didn't care what the men here were talking about, a few glasses of juice were clinking glasses, and they agreed to go horseback riding on the grasslands of Inner Mongolia, go to Tibet to see the snow-capped mountains, and go to Hangzhou West Lake to wear Hanfu and take pictures.
Skewers with beer, it's cool!
Gao Qiao, Xu Zhiliang, Zhang Lin, Xiao Wu, you have a cup, I have a cup, plus two vinegar drinkers, the atmosphere is very warm.
"Xiao Gao, okay, do it!" Zhang Lin immediately filled Takahashi.
"Do it first!" Takahashi did not hesitate, the cup flipped over, and it was dry, and the one who came did not refuse.
After drinking, Takahashi got up and pointed in the direction of the bathroom: "Old iron! Wait for me, relax, come back and keep fighting. ”
Who taught him this, Lao Tie was called?
Zhang Lin and Xiao Wu were stunned for a while, this kid.