Chapter 0357: Big Topic
The regional competition of the Golden Knife Award is carried out in an orderly manner, the competition is becoming more and more fierce, and the harsh scoring makes it more and more difficult to get a perfect score.
Yan Jiejun of Appendix 2 and Su Fengyu of Attachment 1 fell out of the full score camp in the third batch of surgeries, and they made the same mistake.
A young female patient who had a comminuted fracture of the lower end of the humerus was incorrectly selected for the cosmetic suture of the incision and was deducted points.
In fact, the joint area used to be a contraindication to cosmetic sutures, and the advantage of cosmetic sutures is that there are fewer scars, and the disadvantage is that there are no regular intermittent sutures firmly.
Joint surgery requires early rehabilitation training after surgery, and rehabilitation training should generally start the next day after surgery, so as to obtain satisfactory joint function.
The firmness of cosmetic sutures is poor, which cannot meet the needs of early rehabilitation training, and it is easy to cause incision cracking during activities.
Nowadays, the cosmetic suture technology is getting better and better, and if each stitch can hook enough dermal tissue, it can be firm in the early stage, and the original contraindications have become indications.
Yan Jiejun and Su Fengyu have no problems with cosmetic suturing techniques, but unfortunately their mastery of surgical suture techniques is still not comprehensive enough, their understanding of various sutures is insufficient, and they make mistakes in the selection of sutures.
For cosmetic sutures, they use absorbable sutures, which is a mistake that most surgeons tend to make.
Many doctors even refer to absorbable threads as cosmetic threads, which is completely wrong.
At present, the choice of sutures for cosmetic sutures must be non-absorbable slip threads, such as fine nylon threads with needles, which need to be removed after surgery.
Although the absorbable thread does not need to be removed, it is used for sewing the skin, and in the process of absorption, it will produce foreign body reaction and inflammatory reaction, resulting in more obvious scars, which is contrary to the purpose of beauty.
If you have surgery in normal times, this is not a problem, but in competition, you must strive for excellence.
After the third batch of surgeries, those who still maintained full marks were Song Zimo, Su Nanchen, Lin Hao, and Cao Qian.
The strength of the teams in several other provinces in South China is still far behind that of Nandu Province, and there are no teams with full scores.
Lin Hao now has a sense of urgency, three rounds of surgery, but did not get rid of Yang Ping's team, and they are still firmly tied for the first place in the South China Division.
Yang Ping knows very well about Song Zimo's level, this Yizhu will not have an opponent in the regional competition, and when it comes to the national competition, he can sweep for himself.
Unfortunately, more than half of the surgeries in the national competition must be surgeons, and the surgeries in the finals must be done by the surgeons themselves.
So Yang Ping is not in a hurry now, as long as the points are not behind, he does not plan to come forward for the time being, he hurries up to do more important things.
The research on the cultivation of human muscles in the stem cell laboratory has been written.
These days have been spent all here, and the more than 100-page project plan is placed on the desk, which makes people's heads swell.
But there is no way, this big topic involves too many aspects.
Just like building a car, you need to cooperate with many factories, and it is impossible for one factory to make all the parts.
Yang Ping wants to focus on the core technology, although he plans to cooperate with Takahashi, but he will not have much hope for the Japanese, it is only a side alternative.
Yang Ping's main line plan has taken shape, and he needs to find several domestic partners.
The genetic laboratory of Nandu Medical University is the object of his plan to cooperate with the acquisition or synthesis of induced proteins.
Among the topics of using stem cells to cultivate muscle cells, two core technologies have emerged, such as induced differentiation technology and microscaffold technology, and the third core technology in the future is cell structure stabilization technology.
Micro scaffold technology, Yang Ping searched for a long time, and finally found a new company in Pengcheng, called Rubik's Cube New Materials Company, whose 3D printing technology can achieve 15 micron printing, although it is not enough, but it is very promising.
This is a company founded by a group of returnee doctors, and it is not known whether this team has the ability to complete the research and development of miniature stents, which is the only hope for domestic companies.
Only by finding these two partners will there be hope that the project will be completed, and Yang Ping plans to take the time to negotiate one by one.
If the University of Tokyo can cooperate with you and share the technology, you can digest and absorb their technology and improve it, which will shorten the time a lot.
But this kind of hope is not much, Yang Ping is not a person with illusions.
So in the main line plan, you can only gnaw this bone from scratch.
Overtaking in corners, something that has never happened, technology can only be taken step by step, to surpass others, you can only rely on speed.
Scientific research funding is also a big problem, and the first phase of funding needs about 30 million.
This investment is huge, depending on the scientific research fund applied, even if it can be successful, it will be up to one million.
A million dollars is a drop in the bucket, and if you count the follow-up investment funds, this topic is billions.
If there is not enough funds, it will be difficult to run the project, these are very real problems, and he now feels that Xiao Su's words are very correct.
If one day, I can come up with tens of billions of funds casually, I won't worry about this money.
Someone knocked on the door, it should be Song Zimo who had finished the operation.
"I was going to write it, but you're going to have a competition operation, and I've already finished it, so here's the project plan I wrote." Yang Ping pointed to a thick stack of papers on his desk.
Song Zimo browsed the overview: "Why didn't you write about this research fund?" ”
"It's not that I don't write, I can't write it for the time being, it takes 30 million for one issue." Yang Ping said with a smile.
Song Zimo gasped: "The first phase will cost tens of millions, this is a big topic at the level of 100 million yuan, are we a little ---?"
Yang Ping waved his hand: "Just do this topic, I'll raise money." ”
Yang Ping felt that it was the right time to start and could not postpone it any longer.
Start now, wait until the Golden Knife Award wins the championship and gets the reward of the System Space Laboratory, then the work on this topic has already begun, and you can make efforts yourself.
Now Yang Ping feels that if he really wants to do something, it will not work at all without money.
Huawei's annual R&D funds of tens of billions of dollars are smashed into it, and it lasts for more than ten years before Kirin chips come out.
How can other companies have this courage and vision, and this is an investment that cannot be seen.
Compared with this kind of arduous technological research and development, building a few houses can make a lot of money, and everyone likes the latter, making money quickly and coolly.
Duke University, the University of Tokyo, this project is a multi-million dollar investment, and this is all in the early stage. They plan to continue to invest hundreds of millions of dollars in research and development in this project.
"All kinds of scientific research funds, if you can get a million, you will already reach the top. The money of the hospital, the Overseas Chinese Foundation, even if Director Han and Dean Xia agree, it is useless, the money is from the hospital, not personal, and it is impossible to take out tens of millions to do scientific research for you. Song Zimo was worried.
Tens of millions is not a small amount, if it is a business, it is possible to pull venture capital, this kind of scientific research, lose money, who wants to do it.
"I'll figure out how to deal with the money." When Yang Ping had an idea, he had already thought of difficulties.
"30 million, some big professors may not get 30 million in scientific research funds in their lifetime." Song Zimo felt that there was too much money.
"You can do competition surgery with peace of mind, I will do this matter, and the subject must be done." Yang Ping has no doubt.
"Okay, no matter what, I support you, no matter how much money there is, let's figure it out together." Song Zimo fully supported Yang Ping.
He wants to organize everyone to review today's surgery and explain how Yang Ping can raise money together when he is free.
In the WeChat group on the mobile phone, Wei Danian's gene sequencing finally has results.
Some congenital diseases were all excluded, glucose 6-phosphatase deficiency, pyruvate dehydrogenase and carboxylase deficiency, fructose 1 and 6 bisphosphatase deficiency, oxidative phosphorylation deficiency, these known congenital diseases that cause lactic acidosis, did not exist in Wei Danian.
The most advanced genetic testing technology in the country was used, but it was still in vain.
Dr. Wen Yulin's gene sequencing report has written dozens of pages, and has made a detailed report on the sequencing method, the equipment used, and the results of sequencing.
Dr. Wen asked whether to continue to expand sequencing, analyze some precursor molecules and metabolites, and even re-sequence genes, which is a huge undertaking.
Even the genetic sequencing did not find out the problem, is there any need to continue?
Such a rare case is the most precious resource, and it would be a pity to give it up in this way.
However, in the genetic experiment of Nandu Medical University, it is impossible to concentrate all the energy on genetic testing of Wei Danian, and there are still many topics to do.
If it weren't for Su Nanchen's face, how could people be willing to accept such a human task.
Yang Ping suddenly remembered that his system recently had a case push function, and comprehensive medical activities could be carried out on the pushed cases.
He entered the system space, used the function of case push, constantly changed the keywords, narrowed the scope of the push, and finally, through precise push, obtained cases that were very similar to Wei Danian.
Yang Ping conducted the largest examination of this experimental subject, and all kinds of laboratory and instrument inspections were carried out.
However, no clues were found, so he tried to improve the genetic sequencing of the patient.
In reality, there are all examination methods in the system space, and there is no need to queue up to do the examination in the system space, and the resources are all around the case.
A few hours later, the fourth-generation gene sequencing technology was completed, and dozens of pages of gene sequencing reports came out.
After reading the genetic test report, no cause was found.
Yang Ping took a few more genetic sequencing, and this time the huge examination cost him tens of thousands of points.
However, compared to simulated surgery, the consumption of these points is bearable.
Finally, a report showed that there was a mutation in the ATP5F1D gene, and this gene is involved in the function of mitochondria, and it is the mutation of this gene that causes problems in the metabolism of pyruvate, resulting in lactic acid accumulation.
"Can we continue to test, use the fourth-generation gene sequencing technology to focus on the detection of ATP5F1D genes, and do it a few more times, and there may be mutations in the gene."
Yang Ping left a message in the group.
"I'm very sorry, but the fourth-generation sequencing instrument is not available at this time." Dr. Wen said that he regretted that he had been busy with the project recently.
Ten minutes later, Dr. Wen made an OK gesture.
"If we re-do full sequencing, we won't be able to spare resources at all, and we can only do accurate testing of ATP5F1D genes, which can be arranged."
If you look through every household in the whole city to find a lost treasure, the difficulty can be imagined.
Now it's much easier to search just one house.
Yang Ping used this case push function for the first time, and he didn't know if the examination in the system space was instructive in reality.
"We use fourth-generation sequencing technology, and we can get results in a few hours, and we'll start doing it tomorrow." Dr. Wen added.
In fact, Su Nanchen saw the conversation in the group and called Lin Lan, who was willing to continue to help with the test.
Lin Lan is the director of the genetic laboratory of Nandu Medical University, a doctoral supervisor, and an identity: Su Nanchen's future wife.
Lin Lan personally arranged it, Wen Yulin would definitely do it, and Lin Lan was her doctoral supervisor.