Yao Yue, who wore light makeup, came out of the hibiscus, and her sweet and fresh smile actually gave Yang Rui a slight sense of surprise. ｛｝

Yang Rui has always been unable to see whether a woman wears makeup or not, except for nightclub-style heavy makeup, he, like most men, will not study the details of a woman's face to know whether it looks good or not. That's why girls have the meaning of makeup.

However, girls in the 80s obviously didn't understand this. Just two years ago, the "Iron Lady" was still being promoted everywhere in the country, the so-called "women are used as men, and men are used as livestock", before the 80s, it was definitely a compliment, and the royal literati wrote "who said that women are inferior to men" Mulan-style reportage.

With the reform and opening up, women's aesthetics began to awaken, handmade sweaters, flower shirts, red skirts, and bell bottoms gradually appeared, but there are still very few people who wear makeup, especially in prefectures, usually just smear some clam shell oil, and some alabaster cream, even if you have made up makeup, you can get some blush when you get married, which is already considered a heavy makeup.

Yao Yue is a girl from a big city, although the conditions are simple, she is invincible after all, and she dresses up carefully, and it is easy to highlight her bright and lovely girl image.

For Yang Rui, who hasn't seen a TV movie for a long time and hasn't even seen a fashion poster for several months, the impact of a live-action 3D beautiful girl is far better than a 2D animated beautiful girl.

Even more unbearable than Yang Rui is He Cheng, who is a practical assistant.

He Cheng, who grew up in the township, only has a space for activities around Xibao Town, and his only opportunity to see beautiful women is movies.

However, where can the hazy township film film be compared to the living beauty.

He Cheng glanced at the calves under Yao Yue's long skirt, and he had the urge to spray nosebleeds, and the real yàn that he was doing in his hands was completely messed up.

"Beautiful!" Yang Rui naturally praised.

In terms of appearance, he is still a little confident.

The first to blush was really Yao Yue, who bowed his head and said casually: "Yesterday's clothes were dirty." ”

The answer was a bit inexplicable, and I didn't know what I was explaining.

In fact, Yao Yue felt that she was wearing a little too ostentatious.

The red dress under the white coat is as dazzling as a catwalk in a world of green military uniforms and gray cloth clothes.

In terms of the sense of the times, it is equivalent to a certain star wearing a dress when shopping on the Avenue of Xiangsheli in Paris, walking in Tangjiabao Wulipu.

But Yao Yue is also telling the truth. Yao Yue came to Xibao Town, and brought such a change of clothes, as for why she brought her most beautiful clothes bought from Shanghai, this kind of little daughter's mood is insignificant.

Yang Rui felt that it was very good-looking, in line with his own aesthetics, so he naturally looked around her and said with a smile: "What should I do? It is a waste to wear a white coat outside, and if you don't wear a white coat, it is easy to get dirty." ”

"When my clothes are dry, I'll change them back. Yao Yue obviously hadn't received such direct praise, and was more shy in her joy.

Lu Zhi gently nudged him with his elbow and said, "What are you going to do when you come back, you don't stay in the real room all day, you still have to wear your own clothes when you go out." ”

"Don't talk about clothes, what are you doing, can I help?" Yao Yue was embarrassed to continue.

Yang Rui also had no experience in love, so he failed to seize the opportunity to chase and fight, and his thinking was deviated, and he said: "We are verifying the truth and testing the authenticity of several Japanese papers." ”

Yao Yue saw that he was talking about the matter, and immediately felt a lot more relaxed, and when he saw the real preparation in front of He Cheng, he picked it up and looked at it, and said, "You told me about plant extraction?"

"Yes, Japan is a small country, and the animal husbandry industry has never been competitive, so their scientific community has always disliked tissue extraction, and pharmaceutical factories have made some progress in developing tissue extraction methods while actively trying plant extraction, microbial culture methods, and chemical synthesis methods for the sake of profit. Yang Rui roughly explained. In the field of biopharmaceuticals, Japan has seized the opportunity and is developing quite fast, and certain biologics, such as insulin, they occupy the global market. The same is true for coenzyme Q10, Japan was the first to exert force in this field, and at the same time tried plant extraction, microbial culture and chemical synthesis, and selected the semi-plant extraction and semi-chemical synthesis method in the 80s, and gradually implemented the microbial culture method in the 90s, and the money spent was Jinshan Yinhai, in this regard, China in the 80s could not even afford to buy admission tickets.

However, the cost of biopharmaceuticals lies in research and development, and for Yang Rui, who already has the answer, it is not so expensive to replicate a success.

Of course, it is not expensive and relatively speaking, his real room cost more than 30,000 US dollars, and then 20,000 US dollars in cash, this time all invested in it, that is, one or two opportunities to try, if it fails, many investments will not be recovered.

This is still Yang Rui's good luck to catch the last train of the plant extraction method, if it is a microbial cultivation method, there is no need to try, a good fermentation tank can be sold for tens of thousands of dollars, a string of fermenters will cost hundreds of thousands of dollars, Yang Rui got this year's dividends, and it is not enough to copy the money once.

As for the pure chemical synthesis method, which is supposed to be the most advanced and the lowest cost, until 2014, there was no mature industrial production method, and the international big pharmaceutical companies invested tens of millions of dollars in it, which is an invisible bottomless pit.

Although Yao Yue and the others began to enter the real yàn room to help, they did not know about the research and development itself. Yao Yue looked at it for a while, and then asked curiously: "Is it that Japan has already made achievements?

Yang Rui was strange: "Why must Japan have achieved results, so let's copy it?"

"Localization is not the same as copying. Yao Yue was anxious: "It is to fill the domestic gap and save foreign exchange ...... for the country"

"That's not copying. What is the study of localization is the most time-wasting project and money, and this is not military equipment. Yang Rui said in his heart: I am plagiarizing, and I will not copy the patented technology, what is the point of engaging in repeated research.

Lu Zhi also turned her head sideways to look at the real preparation, she still didn't know what Yang Rui was going to do, and asked, "Do you want to do real things on the basis of Japanese research?" ”

In the minds of the Chinese people, foreign research is naturally advanced, and it is naturally extremely difficult to do research on foreign basis.

There's nothing wrong with that.

Real science is to rely on real equipment to complete, without real equipment of real science is rootless, perhaps, occasionally there will be one or two brilliant ideas come out, replacing repeated machinery and equipment, but, if you want to rely on the flash of inspiration for a lifetime, this kind of person should not do real science, should go to sing the little star.

Foreign countries are equipped with advanced equipment, and they can study a wide range of fields. If China wants to do research on the basis of them, it is best to have more advanced equipment, and at worst, it is necessary to have similar instruments and equipment.

For example, the gatekeeper Leeuwenhoek, a Dutchman with no formal education, when he sharpened an excellent lens and saw the world of microorganisms, even if his article "Leeuwenhoek used a homemade microscope to observe some records of skin, meat, bees and other insects" was so crude, that the scientists of the Royal Society had to publish it in the journal of the Royal Society with the help of Leeuwenhoek's microscope to confirm the paper.

No matter how smart the others are, no matter how good the little star is, without a microscope with a magnification of two or three hundred, he is not qualified to do research on the basis of Leeuwenhoek.

The development of modern industry has raised the threshold of science, not lowered, and catching up with the footsteps of developed countries is a difficult and even hopeless job for the Chinese in the 80s.

If Lu Zhi had worked in the university's real room for three or four years, he would definitely not ask such a question.

However, Yang Rui's answer is yes: "We have to avoid the technical barriers of Japanese pharmaceutical companies, well, it can't be called barriers yet, it's just some stumbling blocks, no matter what, we have to use our own way to complete some basic research, which is the basis for doing plant extraction, and then, on this basis, we have to establish our own technical barriers for plant extraction." It's a lot of work, and there are very few researchers, so let's get started. ”

Yang Rui said, and set up the task.

If it were the big pharmaceutical companies in Europe and the United States, they wouldn't do that. They will first use the research results of Japanese pharmaceutical companies, regardless of whether it has a technology patent or not, and then, after the technology that can make money is born on the basis of this patent, they will reverse look for a solution, and it is naturally good to find a solution, and make money happily. If you really can't find a solution, then blatantly infringe, wait for the other party to sue, send dozens of lawyers to accompany the other party to the lawsuit every day, and at the same time happily sell drugs.

Small and medium-sized pharmaceutical companies are afraid of this large vulture. Because this kind of patent lawsuit is often fought for several years, a team of dozens or hundreds of lawyers may spend millions or tens of millions of dollars a year, and small and medium-sized pharmaceutical companies are about to collapse before the court pronounces a verdict, and only large pharmaceutical companies can afford to play it.

Yang Rui is not a pure researcher, he figured out that Guò technology makes money, and he only has an ultra-small biological R&D team, so he must first solve the other party's technical patents, then establish his own technical patents, and then take all the patents and ask for the price.

And all these steps and processes need to be supported by practical and thesis.

If there is no process, just take a result, except for those super-large giants, the NMPA of any country will not pay attention to it. Pharmaceutical companies are not going to make good bids.

Even if it is only a difference in extraction methods, a strict R&D chain must be established.

This is a huge test for Yang Rui, who is strict and lacks funds, and he can only comfort himself, fortunately, it is now the era of biotechnology.

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