Before the fifteenth day of the first lunar month, Frankie came to Xizhaizi Township in Xi County, Nanhu City, Hedong Province.

Along the way, he first flew from London to Hong Kong, then transferred to Beijing, then took a flight from Beijing to Pingjiang, then took a train from Pingjiang to Nanhu, and finally took a car to Xixian County, and then bumped all the way to Xizhaizi Township.

Even though he had been to China several times, it took Frankie four days to see Yang Rui, and under the chubby bags under his eyes, there was deep fatigue.

"Mr. Yang Rui, meet again. Frankie hugged his stomach and sat in the courtyard of the Yang family, looking at the green bricks and dead branches, as well as the red lanterns that had just been hung, and said with a smile: "Your house is very beautiful, very Chinese-style." ”

Yang Rui smiled: "In today's China, you can't see something that is not Chinese." ”

"Since my first visit to China, China has changed a lot. ”

Yang Rui laughed, pointed at Franky, and said, "It should be said that you have learned a lot more than the first time you came to China." Nowadays, Chinese always like to talk about change, but in fact, how many impressive changes can occur in more than a year, but it is just the self-amusement of politicians and politicians. ”

Frankie smiled awkwardly, and immediately felt Yang Rui's sharpness.

This is completely different from the Yang Rui that Frankie had seen before.

In fact, it is also different, Yang Rui, who has a Huarui real room, currently publishes papers that are better than ordinary teachers at Peking University. As far as Cheng dù is concerned, the current Yang Rui has the right to speak in the Chinese academic community.

Not only does he have the right to speak, he has now received a year's dividends, and he still has money in his hand, which makes Yang Rui very confident.

Frankie felt Yang Rui's edge, so he followed his words, talked about the changes, and said with a smile: "I have been to China many times, and in your words, I am a China expert in front of me." However, every time I come to China, whenever I deal with Chinese bureaucrats or journalists, there is an eternal issue, and that is the presentation of results. ”

Frankie said with a smile: "When I first saw it, I thought it was really interesting, in the past few years, China has built a lot of modern factories and buildings, I remember, the first time I went to Tianjin, I saw four factories, very beautiful......

"But after watching too much, I want to vomit?" Yang Rui interjected.

Frankie laughed, "Not yet, but, it's a bit of a waste of time." ”

"Understandably, for a foreigner, it takes a few days for a Chinese to build a building, or whether a new building has been built at an intersection, really doesn't matter." ”

"No, no, no, I still care about China's construction. ”

"I don't care about foreign countries, like Myanmar. Suppose I go to Myanmar, my first concern should be security, secondly, whether I can make money, and thirdly, whether the living environment is comfortable, as for whether Myanmar is developing fast or not, whether the people of Myanmar are happy or not, it has nothing to do with the businessmen who come to Myanmar, right?"

Frankie was reluctant to admit it: "I still hope that China can develop, cooperation is a long-term work, and only when the cooperative opponent develops, can we have better development, this is my view." ”

Yang Rui chuckled and said: "The sun never sets on the empire has flourished for a hundred years, Gibraltar is still a big post station lined with small buildings, except for transportation and service industries, the British Empire doesn't even care about its subjects, let alone the living conditions of distant Far Easterners." ”

Frankie was speechless when he said this.

At the end of the greetings, Yang Ruicai asked him about the specific idea of the development commissioned by Jielikang.

Frankie came to his senses, but his momentum was gone, and he said with little confidence in his first sentence: "We plan to invest a lot of money to acquire a bioproduct company, and at the same time inject capital into your real room to jointly develop the next generation of coenzyme Q10 production process." ”

"What kind of next-generation production process do you want to develop?"

This involves the acquisition of companies, and Frankie hesitated a little, but quickly said: "There are several biologics companies that are researching microbial culture and chemical synthesis, and we are analyzing and evaluating them. Once successful, we hope you will work with our new team to develop a new manufacturing process for CoQ10. ”

"In other words, if you buy a biological product company with microbial culture method, I will cooperate with you to develop a new production process for microbial culture method, and conversely, if you buy a biological product company that uses chemical synthesis method, I will cooperate with you to develop a biological product company with chemical synthesis method?"

"Roughly this means that our team will evaluate which production process is more promising. Frankie gasped and said, "Our team is very experienced and won't let the company's money go to waste." ”

Acquisitions are Jielizena's favorite scientific research method, so they have a first-class scientific search organization, a first-class technical evaluation team, and first-class negotiators.

Investing in China is itself an investment by Jielikang, which specializes in capital mergers and acquisitions.

However, no one can pack a ticket for this kind of thing, at least Yang Rui knows that within 30 years, the future of chemical synthesis is limited.

In fact, since the end of the 60s, various papers on chemical synthesis have appeared, but their synthetic routes, either too costly, or too many impurities, are completely unsuitable for industrial production.

Of course, if there is a huge amount of investment, it is not impossible to break through history if you start to re-study chemical synthesis now.

Yang Rui pondered for a while, didn't say anything, and said, "I still have a job in the real yàn room in China, and I can't leave for the time being." ”

"It's okay to work remotely. "Although the network technology is not yet mature, remote cooperation has been carried out for a long time, especially in European countries, and the proportion of cooperation is very high.

Yang Rui nodded: "If you want me to participate, how will the rights and interests be distributed?"

This is to the core.

Frankie picked up his spirits and asked, "Would you like to contribute?"

"How about contributing, and how about not contributing?"

"If you make a contribution, you can own a proportionate stake in the acquired company, and we can increase the proportion of your stake in the project you are involved in. ”

This is a partnership business, if the company acquired by Jielikang has a future, or the acquired company has achieved remarkable results in the next project research, Yang Rui can naturally make a small profit, but if it has no future, it will inevitably lose back.

Yang Rui received $4 million in dividends, which was used for personal consumption or to support the current real room, which was quite easy, but it was really a drop in the ocean for international acquisitions.

The 80s was the stage of rapid development of biologics companies, most of which were valued at very high valuations, with small companies of $20 million or even $50 million abounding, and an American biotech company with 20 researchers making some achievements could easily ask for hundreds of millions.

Coenzyme Q10 is considered a partial industry in biological products. In Japan, coenzyme Q10 is included in the list of medicines, but the United States and the United Kingdom are still dietary supplements, which are what the Chinese call health medicines. The price of such a company's technology is relatively low, but it will cost millions of dollars at least, and counting the other value of the company, Yang Rui will get 20 or 30 percent of the shares at most.

Of course, with Jielikang's temperament, it is also very possible to find an M&A company, spend hundreds of millions of dollars to buy a company back, and then dismantle what you want and sell what you don't want.

This kind of game is a headache for people who can read the accounting alone.

Yang Rui shook his head and said, "Let's take the part that doesn't contribute." ”

"Zeliconia can get $500,000 in sponsorship, but you have to make sure that you have smooth communication with the new company and that the results belong to Zelizen. Frankie's new proposal is a contract that professors at American universities often get, and for the vast majority of researchers, all they need is fame and results, and the financial benefits of the results themselves, people don't care.

Researchers who want to make money either join a large company directly, or after gaining prestige and fame, join a large company or even start a business directly.

Having a company willing to sponsor research is a very fortunate thing for researchers in any country. After all, there is such a thing as a successful research before it can be fruitful, if it is not successful, the money is wasted, and many times, the research is often between success and unsuccess - the researcher can still write a paper according to the real yàn, and the unsuccessful real yàn also spends money, which is also valuable. And investors are naturally lost.

Yang Rui also got such a pure sponsorship contract because of his two successful collaborations with Jielikang and his outstanding research capabilities in the Sinovel room.

In a university in the United States or the United Kingdom, such a contract can also attract a few pairs of envious eyes.

For pure researchers, it is perfect to be sponsored by a large company, after all, even a Nobel laureate cannot guarantee the success of his next project.

To be more precise, most of the Nobel laureates are good at cheating money, and the perfect projects they say are the most money-trapping. Sometimes, they will even give a skin to the basic research they want to do, and then use it to exchange it for sponsorship, and in the end, even if they make something, the sponsoring company can't cash it out.

If he can't be sure of success, Yang Rui is willing to accept pure sponsorship, anyway, the money is given to himself, and the equipment and so on bought with this money do not have to be returned. If it's a fund that doesn't have a lot of scrutiny, such as China's Natural Science Foundation before 2010, it's okay to use the money to buy a car and drive. Even if it is a relatively strictly managed fund, it is reasonable to lease a Mercedes-Benz BMW or something for a long time.

However, Yang Rui's real strength lies in his certainty that he can succeed. Although the paper in his mind cannot be used for factory production, as long as there are research ideas and some papers on technological processes, it is not difficult to repeat each production link, at least it is much smaller than acquiring a company and researching it from scratch.

If JieliZena chooses the chemical synthesis method, the difficulty is even more different.

So, just when Yang Rui thought for a long time, so much so that Frankie thought he was going to agree, Yang Rui said: "I'm still willing to be a ...... Contractor. ”

It's a bit of an American word, and Frankie immediately understands it, thinks for a moment, and says, "Don't you want to work with the other teams?"

"I have my own team and it's excellent. Yang Rui smiled confidently.

"Two teams are working on this project at the same time, we can accept it, do you want to get a share share?" In pharmaceutical companies, it is common for two or even four teams to do the same project at the same time, because no matter how smart the manager is, it is difficult to determine which route is correct, just like the research and development of coenzyme Q10 can have chemical synthesis and microbial culture, and in the chemical synthesis method and microbial culture method, there will be multiple routes, researchers will choose the most opportunity and the best route to develop and advance, but which one can ultimately achieve the goal, no one can say.

So, multiple teams working on a project together is like a venture capital investing in multiple companies at the same time, it costs a lot of money, but it increases the success rate, and as long as one route is successful, all the costs can be recovered.

On the other hand, multiple teams don't just spend more money, they will always come up with something that, if not immediately cashed out, may still receive money one day as long as they apply for a patent. For example, Viagra was originally used as a heart medicine, but the effect was average, but it was used to resist ED, but it became a "blockbuster" with annual sales of more than 1 billion.

Yang Rui nodded and said, "You contribute 400,000 US dollars, and we will each take half of the results." ”

Different from the sponsorship of 500,000 US dollars, if Yang Rui develops alone, he first saves the cost of the cooperative team, or in other words, it is equivalent to an additional R&D team. Normally, Yang Rui's energy and brain power will increase.

On the other hand, the $500,000 sponsorship is only an upfront investment, and if it is exactly halfway through, the future is bright but the results are not achieved, whether Jielizeneca should increase the investment, or must increase the investment, otherwise, the research team has the right to take what it already has and find other investors to continue the research.

Many research teams use this method to hedge investors' money, and it is not uncommon to find legends of $500,000 and $50 million.

In addition to 400,000 US dollars, Jielikang does not need to consider the later investment, if the prospects are bright and the results are not obtained, Yang Rui has to invest his own money, or sell his own shares to find other investors to invest. Of course, if JieliZeneca is willing to continue to invest, Yang Rui also has to let all or part of his shares, which is equivalent to an installment sponsorship contract that JieliZen has the right to choose.

Of course, the same amount of money, only half of the shares, did not satisfy Frankie, and the two of them bargained back and forth.

The sound of English in the yard quickly attracted curious neighbors. Because Comrade Yang Feng is the secretary of the township party committee, everyone finally did not block the door of the house, just stood in the corner of the wall one by one to listen to the movements inside, and those who didn't know thought they were queuing up to give gifts to the Yang family.

Rui's mother didn't know what Yang Rui was talking about, so she felt that Bei'er had face, and when she mentioned the vegetable basket, she went out for a while.

……