"Professor Yu, can't USTC use guò solaneol to chemically synthesize coenzyme Q10?" Director Hai held the phone, sweating on his hands.

The voice of the phone was a little distorted, but it was clear: "Our institute has no special research in this area, but as far as I know, there is no precedent for factory this technology in China." It seems that the Beijing Institute of Biological Products has done a similar project, you can inquire about it. ”

"I've called, and they've given up on the project. Director Hai squeezed the phone, feeling strange.

Even the project that the Beijing Institute of Biological Products did not make was actually made by Yang Rui, if it were not for the precedent of the WestJet factory, he would definitely have met a liar.

But if it weren't for the scammers, the technology would be too powerful, and it's no wonder that Jielizen easily agreed to the share reduction, and unlike the last time, it asked for technology transfer.

It seems that they simply did not discuss the issue of technology transfer, knowing that the value of technology was too high.

Perhaps, it is hoped that after the factory is put into production, it will steal from it?

Director Hai was amused by his own thoughts, and then felt proud, foreigners stealing teachers from China, this kind of story, domestic magazines and newspapers like to write, but only people in the professional field know how big the gap between China and foreign countries is now.

The whole 10 years of stagnation has brought backwardness not only for ten years, but also for twenty or thirty years, and in the field of biotechnology, China's technology is still staying, or in other words, the peak of China's technology is staying in the artificial synthesis of insulin.

However, synthetic insulin in the 0s was no longer uncommon in the 80s, but in China, there are not many people who can replicate this reality.

Professor Yu let out a natural "oh" on the other end of the phone and said with a smile: "It's a pity to give up, and it's not surprising." In the past two years, too many projects have been cut, and coenzyme Q10 is not an important drug related to the national economy and people's livelihood. ”

"Then you say, if USTC or Beijing Institute of Biological Products restarts the project, how long will it take to see results?"

"Our school is not going to do this project. Professor Yu's hearty voice came, and he said with a smile: "The current goal of our institute is to keep track of the latest international basic research, such as biological macromolecules, stem cells, gene functional omes, etc., and the production of coenzyme Q10 is of an applied nature, even if there is a national funding, it may not be able to spare manpower." ”

"How long do you think it will take for the Beijing Institute of Biological Products to restart the project? ”

"It's hard to say. ”

"Professor Yu, we are so familiar with each other, you can analyze it, and I will know how to make a decision. Director Hai said a small word, although he is in charge of the sales of raw materials and refined chemicals across the country, there are four departments under his hands, more than 20 people, one of whom can do research, whenever he encounters this kind of thing, he is looking for a familiar professor to ask.

Professor Yu was also willing to maintain a mutually beneficial relationship with Director Hai, and after a moment of silence, he said: "I can't do analysis for others, so I'll just guess it, if this technology is restarted, whether it can produce results is actually a bit of luck." ”

"How?"

There are many reasons for this, the main point is that the nature of coenzyme Q10 is relatively special, and its intermediate is not stable enough, so the real yàn room technology cannot be directly used in the factory, and the factory production is equivalent to opening up a new way, through guò solanesol to produce substance A, and then convert it into substances B, C, d, and finally to coenzyme Q10, the ABCD in it, all have to be stable dìng substances, do you say it's easy or not?" Professor Yu said in a somewhat teaching tone to students.

Director Hai listened very carefully and asked: "I don't know much about technology, so I just want to ask, isn't it the same for other factory production technologies?"

"Not all, some of the real room technology can be used directly in the factory, because the route it takes in the real room, the intermediate products it passes through, are themselves suitable for factory use. I'll make an analogy, chemical synthesis is like going from one place to another, the intermediate product is to pass the bridge, there are 4 intermediate products, that is, there are four bridges, the real yàn room technology is like a person walking, any bridge can be, pontoon bridge is also OK, wooden bridge is OK, stone bridge is OK, researchers do not force it, when encountering wooden bridges, use wooden bridges, use stone bridges, use pontoon bridges. Factory production is like a truck pulling goods, its conditions are harsh, at least it has to be Shiqiao Pavilion, if the scale of the factory is large, it has to be a railway bridge, do you understand?"

"That is to say, some of the real yàn room technology, just encountered above the stone bridge, coenzyme Q10 technology, are all wooden bridges and pontoon bridges?"

"That's what it means, but that's not all, if you think about it, even if the first three bridges are stone bridges, and the fourth bridge is not a stone bridge, you still can't get through, you have to go back to the third, or the second, or even the first bridge, and start over, if you can't find the way to the whole stone bridge, this synthetic solution will never work. The semi-chemical synthesis of coenzyme Q10 has been around for a long time, indicating that many people have explored the road, but it is not possible now, indicating that it is very difficult, and you want to know how long it will take to make it, I don't think anyone dares to guarantee it. ”

Director Hai had a plan in his heart, and at the same time, he was once again amazed by Yang Rui's level.

He doesn't know much about technology, but he is a knowledgeable person, and if one technical success is luck, the second time it is difficult to say so.

However, Director Hai didn't see anything after all, so he asked tentatively: "Professor Yu, then if I say that a student has made this technology, what do you think?"

"Which school?"

"I haven't verified. Director Hai told a small lie, and then said: "Do you think that a person, a student, has solved this factory chemical synthesis route, do you think it is possible?"

There was silence on the other end of the phone for a full ten seconds before Professor Yu's voice continued: "If you have the right equipment, instruments, systematic training, knowledge reserves, and luck, it is not impossible for one person to do it." Students are also strong and weak, not that they can't do it, but it's not easy...... Let me say more, if someone can complete this technology, whether it is a student or a farmer, the domestic research institute should be able to be arranged with an open door.

The director of the sea department had a plan in his heart and said, "I understand, if it is confirmed that the technology is true, are you interested in taking a look?"

Jielizen reduced its stake from 50% to 45%, not simply by 5%, but by giving up a controlling stake. If Yang Rui and Guoyi Foreign Trade unit, they can decide the direction of the new joint venture factory.

Director Hai felt that if Yang Rui was pulled into the system and entered a certain research institute, the control of foreign trade of traditional Chinese medicine would be greatly improved.

This idea had been considered by Director Hai since the days of the WestJet factory, and now it has only strengthened it even more.

He felt that with Professor Yu's help, whether it was the research institute or Yang Rui, he would be able to speak better.

Professor Yu was also curious by what he said, and said: "You have confirmed the technology, I must take a look, if possible, you can come to the University of Science and Technology of China, show our students and teachers, if it is not convenient, I will take the time to come." ”

"We're going to show you how to get you to come here. Director Hai laughed and said nicely.

Just like Shen Pinghui, the director of the Pingjiang Institute of Biotechnology, when necessary, he will appear in front of the provincial leaders as an authority on biology in the province, the University of Science and Technology of China, which is currently known as China's first university, is not lagging behind on the road of connecting academia with politics, and Professor Yu's reputation in the circle is also quite high.

This kind of bull-level person, and ordinary little professor, are two levels, and Director Hai must also be careful.

After ending the phone call with Professor Yu, Director Hai An waited for two days and finally met Trapp, the chief representative of Zeliconia who flew from the UK.

He brought four of his men this time, as well as more than a dozen kinds of instruments that can fit a jeep, how difficult it is to borrow instruments and equipment in China, Trapp has learned from the last time he came, and he doesn't want to experience it again this time.

In many cases, domestic research institutes do not give people direct use of instruments, but let you list the requirements, and then send a special person to operate, for fear that any mistake will damage the instrument.

Trapp is not accustomed to this approach, so he simply loaded a truckload of equipment from Hong Kong and prepared to donate it to several universities in China when it ran out, which is also one of the various agreements for Zelicona to invest in China.

Trapp sent the instrument to Xibao Middle School, and then worked with Yang Rui to refine the real yàn of solanesol.

In terms of some key steps, Yang Rui still refuses to disclose them, but the number is smaller than the last time, after all, he is now also a person who has the money to register patents.

The real yàn of refined solanesol is very smooth, and Trapp even gave a full score evaluation, which gave great confidence to Jielikang and Chinese medicine foreign trade.

Director Hai and Frankie couldn't wait to sign the agreement with Yang Rui on the new joint venture plant.

Since Sinovel Pharmaceutical Company is a Hong Kong company, the new joint venture factory has become a tripartite joint venture between China, Britain and Hong Kong, and big names have taken off.

However, in order to minimize the hassle of selecting a crude solanesol plant, the three parties did not publicize the agreement to the outside world, but let Director Hai negotiate with each company first.

Although the foreign trade of traditional Chinese medicine also has its own technical department, but they mainly do foreign trade, to say that understanding technology is to understand, proficient in technology is impossible, so the director of the sea pulled Yang Rui, and various enterprises were in contact.

The production of solanesol by plant extraction, even if it is crude solanesol, requires thousands of tons of raw materials, and to supply a refined solanesol factory, at least three or more crude solanesol factories are required, and more than five is naturally better.

Of course, the profits generated by crude solanesol will also be shared by the foreign trade of traditional Chinese medicine and related enterprises.

Since it is the money made by the foreign trade of traditional Chinese medicine, Director Hai is also extra attentive and tirelessly conducts in-depth exchanges with various enterprises, not only that, but he also sent people to Yunnan and other major tobacco provinces to understand the local tobacco production and marketing.

For Yang Rui, Director Hai's attitude is also kind to the extreme.

First of all, Yang Rui has won a certain political and economic status, that is, a Huarui pharmaceutical company, although the empty shell is like a leather bag company, but it has a number of patents in it, and it will not be ignored anywhere in the country. In recent years, it's not that you can't imagine that you can register a company in Hong Kong to be a Hong Kong-funded enterprise, but you can't take out foreign exchange to do this kind of thing.

Secondly, Director Hai has become more and more aware of the difficulty of semi-synthetic production of coenzyme Q10, which is something that even the Beijing Institute of Biological Products cannot guarantee to make.

Thirdly, it was because Director Hai really needed someone to help him judge the conditions for the construction of a crude solanesol plant. In this regard, foreigners are not credible, and the level of his subordinates is very average, Yang Rui has become the best choice.

Although he couldn't give Yang Rui a high reward, Director Hai waited for Yang Rui to be as comfortable as possible, and the first thing he did was to move Yang Rui from the front building to the back building of the Pingjiang Hotel.

At the same time, savvy local companies seem to be sensing something.

……